Sponsor(s):
National Institute of Mental Health (NIMH)
- Condition(s):
-
Eating Disorders
Bulimia nervosa
Binge-eating disorder
Bulimia
Eating Disorder
Obesity
Binge Eating Disorder
Purpose:
This study will determine whether the disturbances in cholecystokinin release and gastric
emptying that occur in people with binge eating disorder are similar to those that occur in
people with bulimia nervosa.
- Eligibility:
-
- Minimum Age:
- 18 Years
- Maximum Age:
- 60 Years
- Accepts Healthy Volunteers:
- Yes
Inclusion Criteria:
For all participants:
- Obese (body mass index (BMI) greater than 35 kg/m2)
For participants with BED:
- Meets DSM-IV criteria for BED
- BED duration of at least 1 year
For healthy participants:
- Weight close to that of participants with BED
Exclusion Criteria for all participants:
- Current or past diagnosis of BN, or any binge eating or self-induced vomiting
- Significant medical illness
- Current or lifetime history of schizophrenia, bipolar disorder, or other psychotic
disorder as defined by DSM-IV-TR
- Current DSM-IV-TR diagnosis of organic mental disorder, factitious disorder, or
malingering
- History of a personality disorder (e.g., schizotypal, borderline, or antisocial) that
might interfere with assessment or compliance with the study procedures
- At risk for suicide
- Currently taking psychotropic medication or medication that is known to affect
appetite or gastric functioning
- History of drug or alcohol abuse within the 3 months prior to study entry
- Pregnant, planning to become pregnant, or lactating
- Anemia
Other Location(s):
New York, New York United States
Terms:
This is an abstract courtesy of ClinicalTrials.gov,
a service of the US National Institute of Health Developed by the National Library
of Medicine. ClinicalTrials.gov provides regularly updates information about federally
and privately supported clinical research in human volunteers.
