Clinical Trials

Sponsor(s): National Institute of Mental Health (NIMH)

Condition(s):

Eating Disorders
Anorexia
Bulimia nervosa
Anorexia Nervosa
Binge-eating disorder
Bulimia
Eating Disorder
Obesity
Binge Eating Disorder

Purpose: This study will use a sipping and spitting exercise to better understand the brain's response to food intake in people with eating disorders.

Eligibility:

Minimum Age:

16 Years

Maximum Age:

45 Years

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

For participants with bulimia nervosa:

- Meets DSM-IV criteria for bulimia nervosa

- Duration of illness is 1 year

- Self-induces vomiting

- Weighs between 85 and 120% of ideal weight

For participants with anorexia nervosa:

- Meets DSM-IV criteria for anorexia nervosa (amenorrhea will not be required for study
inclusion)

- Medically stable

For participants with binge eating disorder:

- Meets DSM-IV criteria for binge eating disorder

- Duration of illness is 1 year

- Body Mass Index (BMI) is at least 30

For healthy participants:

- Weighs between 80 and 120% of ideal weight

Exclusion Criteria:

For participants with anorexia nervosa, bulimia nervosa, or binge eating disorder:

- Significant medical illness

- At risk for suicide

- Currently taking medication

- History of drug or alcohol abuse within 6 months prior to study entry

- Pregnant or breastfeeding

- Axis I psychiatric disorder requiring pharmacotherapy

- Axis I psychiatric disorder that could impair ability to participate in the study
(e.g., mania, psychosis)

- Comorbid binge eating disorder and an Axis I illness other than major depression

For healthy participants:

- Current or history of psychiatric illness

- History of any eating disorder

- Significant medical illness

- Currently taking medication

- History of drug or alcohol abuse within 6 months prior to study entry

- Pregnant or breastfeeding

Other Location(s): New York, New York United States

Terms: This is an abstract courtesy of ClinicalTrials.gov, a service of the US National Institute of Health Developed by the National Library of Medicine. ClinicalTrials.gov provides regularly updates information about federally and privately supported clinical research in human volunteers.